https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:14141 Wed 11 Apr 2018 14:22:02 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:14145 Wed 11 Apr 2018 13:46:42 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:4358 90% (p=.14), the duration of gametocyte carriage increased from 3 to 22 weeks (per 1000 person‐weeks) between 1998 and 2002 (p≺.001). The dhfr and dhps mutations associated with sulfadoxine‐pyrimethamine resistance were the most important drivers of the increased gametocytemia, although these mutations were not associated with increased pretreatment asexual parasite density or slower asexual parasite clearance times. The geometric mean gametocyte duration and area under the gametocyte density time curve (per 1000 person‐weeks) were 7.0 weeks and 60.8 gametocytes/μL per week, respectively, among patients with wild‐type parasites, compared with 45.4 weeks (p=.016) and 1212 gametocytes/μL per week (p=.014), respectively, among those with parasites containing 1–5 dhfr/dhps mutations. Conclusions: An increased duration and density of gametocyte carriage after sulfadoxine-pyrimethamine treatment was an early indicator of drug resistance. This increased gametocytemia among patients who have primary infections with drug‐resistant Plasmodium falciparum fuels the spread of resistance even before treatment failure rates increase significantly.]]> Wed 11 Apr 2018 13:43:20 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:15340 Wed 11 Apr 2018 09:43:32 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52174 Wed 04 Oct 2023 11:03:18 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46728 95% had at least 2 vaccine doses. Attack rates were 295 of 535 (55.1%) and 102 of 189 (54.0%), respectively (mean, 5 days postevent). At the ball, attack rates increased with time since vaccination: 12.5% among those vaccinated 1–2 months previously and 68.0% among those vaccinated ≥3 months previously; such differences were not found at the nightclub. Recent vaccination prevents Omicron infection, but is time and setting dependent, emphasizing the importance of nonpharmaceutical public health measures in addition to vaccine booster doses to maximize protection in high-risk contexts.]]> Tue 29 Nov 2022 11:55:33 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44136 Sat 08 Oct 2022 12:43:28 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42170 Fri 26 Aug 2022 07:58:29 AEST ]]>